Police have closed two lanes on the A45 in Northampton while they deal with a smash involving a lorry carrying chemicals.
The stretch of carriageway eastbound is partially blocked between Riverside and Barnes Meadow with firefighters on the scene to asses the damage to the HGV.
The crash was reported at just after 7.30pm.
A Northamptonshire Police spokesman said: “The lorry involved is carrying chemicals which our colleagues at Northamptonshire Fire & Rescue Service are assessing to make safe.
“There are some delays in the area at the moment and we are working hard to get the road fully reopened.”